Friday, May 14, 2010

what are three major themes you would identify that connect the various topics discussed in the course

This semester we have discussed basic chemical principles and looked at the nature of different molecules that make up all living creatures. Metabolism brought all of this together and showed how the bulk of chemical reactions of biomolecules function within us all and is the basis for life itself. But in order for metabolism to occur structures need to be formed so that open systems can be achieved and biomolecules can be used efficiently. This is why DNA replication and protein synthesis are two other important process we have learned and all three of these connect with all the topics we have discussed.
DNA replication forms a template strand that is transcribed into RNA and is then translated into specific proteins and it is involved and influences all other processes within an organism. It designs the proteins needed for metabolism, the enzymes used to catalyze metabolic reactions and designs the systems needed for these reactions occur.
Proteins are like the, “local handy man” and seem to be able to do any task given to them. They are involved in every process even the synthesis of themselves. Proteins work in the building and repairing of body tissues, regulates body processes and formation of enzymes and hormones. Our body needs proteins for the purpose of maintenance and healthy growth.
Metabolism, DNA replication and the synthesis of proteins are topics that seem to come up over and over again in all my classes; Biochemistry has only taken them and really gone into depth as to how they work. Now I know that transcription and translation factors are extremely important in synthesis of new proteins. Apparently I only knew the basics behind synthesis (which was fine with me), DNA replicates by DNA polymerase binding, A-T, C-G and U is involved in RNA translation and synthesis of proteins. Now I know it is extremely complicated and that there important protein factors that must bind too DNA first before Polymerase is even in the picture.
In biochemistry it seems every class I am learning about a new protein and how important it is. Transcription and translation factors of pre-initiation complexes, to Enzymes and co-enzymes in catalyzing reactions of metabolic pathways each week there is a new protein to understand.
Metabolism has been the same case. I knew the basics glycolysis and the metabolic pathway of glucose to form ATP NAD and FAD. Now I know what reaction occurs in steps of glycolysis and the enzymes used for these different reactions if they are exorgonic or endorgonic reactions. We also went into greater detail as to how lactate is synthesized back into glucose which I found very interesting because I didn’t know that these reactions in glycolysis for the most part can go both ways.

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